Sunday 19th of September 2021
 
expressExpression - Publications

Original Manuscripts
  • Quayle, L.A., Spicer, A., Ottewell, P.D., Holen, I. (2021). Transcriptomic Profiling Reveals Novel Candidate Genes and Signaling Programs in Breast Cancer Quiescence and Dormancy. Cancers (under revision).
  • Tulotta, C., Lefley, D., Moore,. C., Amariutei, A., Spicer, A., Quayle, L., Hughes, R., Ahmed, K., Cookson, V., Evans, C., Vadakekolathu, J., Heath, P., Francis, F., Pinteaux, E., Pockley, A., Ottewell, P.D. (2021). IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. NPJ Breast Cancer (under revision).
  • Quayle, L.A., Ottewell, P.D., Holen, I. (2018). Chemotherapy Resistance and Stemness in Mitotically Quiescent Human Breast Cancer Cells Identified by Fluorescent Dye Retention. Clin Exp Metastasis, 35(8): 831-846.
  • Quayle, L.A., Pereira, M.G., Scheper, G., Wiltshire, T., Peake, R.E., Hussain, I., Rea, C.A. & Bates, T.E. (2017). Anti-angiogenic drugs: direct anti-cancer agents with mitochondrial mechanisms of action. Oncotarget, 8 (51): 88670-88688.
  • Quayle, L., Ottewell, P.D., Holen, I. (2015). Bone Metastasis: Molecular Mechanisms Implicated in Tumour Cell Dormancy in Breast and Prostate Cancer. Curr Cancer Drug Targets. 15: 469-480.
Book Chapters
  • Holen, I. and Quayle, L.A., (2020). Stem cell niches in bone and their roles in cancer metastasis. Advances in Stem Cells and their Niches. Elsevier. 5: 35-62.
  • Ottewell, P.D. and Quayle, L.A. (2019) Tumor Dormancy in the Bone. Encyclopaedia of Bone Biology. Elsevier. 166 - 179.
Conference Proceedings
  • Quayle, L., Ottewell, P.D., Holen, I. (2018), Therapeutic Resistance and Stemness in Mitotically Quiescent Human Breast Cancer Cells. 1st UK Interdisciplinary Breast Cancer Symposium 15th – 16th January 2018; Manchester, U.K. Breast Cancer Res Treat. 167:309–405: Abstract P10.12.
  • Quayle, L., Park, S., McDonnell, D.P., Ottewell, P.D., Holen, I. (2017) Targeting ERR-α Regulated Lactate Metabolism Eliminates Drug-Resistant Breast Cancer Cells. Proceedings of the 2016 San Antonio Breast Cancer Symposium 6th – 10th December 2016; San Antonio, TX, U.S.A. Cancer Res. 77(4 Suppl): Abstract P3-07-14.
Oral Presentations at Conferences
  • Quayle, L., Ottewell, P.D., Holen, I. Gene Expression Signatures Associated with Mitotic Quiescence in Breast Cancer. 23rd Cancer Research UK Beatson International Cancer Conference 'Talk to the Niche: Understanding the Biology of the Metastatic Niche', 1st - 4th July 2018, Glasgow, Scotland.
  • Quayle, L., Ottewell, P.D., Holen, I. Therapeutic Resistance and Unique Stemness Define Mitotically Quiescent Sub-Clones in Human Breast Cancer. 1st Yorkshire Breast Cancer Symposium, 9th June 2017, York, England.
  • Quayle, L., Jones, M., Ottewell, P.D., Holen, I. Mitotically quiescent human breast cancer cells are characterised by multi-drug resistance and a unique stem cell-like phenotype. Sheffield Cancer Research Day, 8th March 2017, Sheffield, England.
  • Quayle, L., Park, S., McDonnell, D.P., Ottewell, P.D., Holen, I. Inhibiting ERR-α Regulated Lactate Metabolism Eliminates Drug-Resistant Breast Cancer Cells. 7th Annual Mellanby Centre Research Day, 2nd December 2016, Sheffield, England.
  • Quayle, L., Ottewell, P.D., Holen, I. Finding New Ways of Stopping Breast Cancer from Spreading to the Skeleton. 12th Annual Sheffield Medical School Research Meeting, 16th – 17th June 2016, Sheffield, England.
  • Bates, T.E., Quayle, L. Repurposing Established Drugs for Cancer Chemotherapy. 6th APS International PharmSci Conference, 7th – 9th September 2015, Nottingham, England.